BAK1 Antikörper (AA 1-50)
Kurzübersicht für BAK1 Antikörper (AA 1-50) (ABIN483832)
Target
Alle BAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Spezifität
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Bak Antibody detects endogenous levels of total Bak protein.
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Bak.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
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Kommentare
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Unigene-Number: Hs.485139 (NCBI Gene Symbol: BAK1)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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: "Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells." in: Cell death and differentiation, Vol. 19, Issue 12, pp. 1928-38, (2012) (PubMed).
: "Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK)." in: PLoS ONE, Vol. 7, Issue 4, pp. e34549, (2012) (PubMed).
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- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Andere Bezeichnung
- Bak
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Hintergrund
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Synonyms: Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like 7 protein, BAK1, BAK, BCL2L7
NCBI Gene Symbol: BAK1
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Molekulargewicht
- 23 kDa
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Gen-ID
- 578
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OMIM
- 600516
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UniProt
- Q16611, Q13014
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Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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