ABL1 Antikörper (pTyr245)
Kurzübersicht für ABL1 Antikörper (pTyr245) (ABIN482036)
Target
Alle ABL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 196-245, pTyr245
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Spezifität
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c-Abl (Phospho-Tyr245) Antibody detects endogenous levels of c-Abl only when phosphorylated at Tyr245.
PhosphorylationH:Y245 M:Y245 R:Y245
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human c-Abl around the phosphorylation site of Tyr245.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000
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Kommentare
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Unigene-Number: Hs.431048 (NCBI Gene Symbol: ABL1)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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Andere Bezeichnung
- C-Abl
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Hintergrund
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Synonyms: ABL1, JTK7, Proto-oncogene tyrosine-protein kinase ABL1, c-ABL, p150
NCBI Gene Symbol: ABL1
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Molekulargewicht
- 122 kDa
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Gen-ID
- 25
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OMIM
- 189980
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UniProt
- P00519
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Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
Target
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