DPP4 Antikörper

Produktnummer ABIN457416

Der Maus Monoklonal anti-DPP4 Antikörper (Klon BA5b) (ABIN457416) detektiert spezifisch DPP4 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DPP4 Antikörper (ABIN457416)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: BA5b

Produktdetails anti-DPP4 Antikörper

Verwendungszweck: Anti-Hu CD26 Purified

Kreuzreaktivität (Details): Human

Produktmerkmale: The mouse monoclonal antibody BA5b recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: A human T cell clone

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-2 μg/mL, positive control: human peripheral blood leukocytes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Andere Bezeichnung: CD26

Hintergrund: Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP

Gen-ID: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity