ARPC2 Antikörper (N-Term)

Produktnummer ABIN406714

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARPC2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen und Pferd.Es wurde in 1 Publikation zitiert.

Kurzübersicht für ARPC2 Antikörper (N-Term) (ABIN406714)

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARPC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARPC2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MVLNVYCCFF QISDIQTMKI NQTILKEFIL VGFSVYPHVQ TFLFVVFFCL

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ARPC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARPC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 300 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ARPC2 Antikörper (ABIN406714)

Al Ghouleh, Rodríguez, Pagano, Csányi: "Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration." in: International journal of molecular sciences, Vol. 14, Issue 10, pp. 20220-35, (2013) (PubMed).

Details zu ARPC2

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Andere Bezeichnung: ARPC2

Hintergrund: ARPC2 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of ARPC2, the p34 subunit, has yet to be determined. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Alias Symbols: ARC34, PNAS-139, PRO2446, p34-Arc
Protein Interaction Partner: SUMO2, UBC, ARPC5L, AARSD1, PUS1, NIF3L1, THG1L, NSUN2, SH3GLB1, LAP3, TPRKB, TNPO3, ANP32B, ACTR2, ACTR3, ARPC1B, ARPC3, ARPC4, ARPC5, TOM1L1, FUBP1, SUMO1, TPD52L2, SH3GL1, RPA2, RPA1, RANGAP1, PRKACB, PRKACA, PPP2R5D, PFDN5, PPP1R12A, MTR, METTL1, CALU
Protein Size: 300

Molekulargewicht: 33 kDa

Gen-ID: 10109

NCBI Accession: NM_005731, NP_005722

UniProt: O15144

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization