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MAP1LC3A Antikörper

MAP1LC3A Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 166AT1234 unconjugated
Produktnummer ABIN387792
  • Target Alle MAP1LC3A Antikörper anzeigen
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    Reaktivität
    • 212
    • 105
    • 86
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 175
    • 43
    • 2
    Maus
    Klonalität
    • 166
    • 54
    Monoklonal
    Konjugat
    • 109
    • 18
    • 15
    • 14
    • 14
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MAP1LC3A Antikörper ist unkonjugiert
    Applikation
    • 198
    • 95
    • 74
    • 47
    • 33
    • 32
    • 29
    • 14
    • 14
    • 14
    • 11
    • 10
    • 9
    • 6
    • 5
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This LC3 antibody is generated from mouse immunized with a full length recombinant protein of human LC3 (APG8).
    Klon
    166AT1234
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product MAP1LC3A Primärantikörper
  • Applikationshinweise
    WB: 1:8000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Haltbarkeit
    6 months
  • Ichikawa, Alves, Pfeiffer, Langa, Hernández-Santana, Suzuki, Prehn, Engel, Henshall: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." in: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).

    Griesser, Vemula, Raulien, Wagner, Reeg, Grune, Fedorova: "Cross-talk between lipid and protein carbonylation in a dynamic cardiomyocyte model of mild nitroxidative stress." in: Redox biology, Vol. 11, pp. 438-455, (2017) (PubMed).

    Chen, Fang, Su, Hsu, Yang, Huang: "Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia." in: OncoTargets and therapy, Vol. 9, pp. 4453-64, (2016) (PubMed).

    Graham, Kaza, Klocke, Gillespie, Shevde, Carroll, Roth: "Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma." in: Journal of neuropathology and experimental neurology, Vol. 75, Issue 10, pp. 946-954, (2016) (PubMed).

    He, Yuan, Qi, Zhang, Wang: "Atorvastatin induces autophagic cell death in prostate cancer cells in vitro." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4403-8, (2015) (PubMed).

    Vlahava, Eliopoulos, Sourvinos: "CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism." in: Cellular signalling, Vol. 27, Issue 6, pp. 1253-63, (2015) (PubMed).

    Hsin, Ou, Wu, Jan, Hsiao, Lin, Ko: "GMI, an Immunomodulatory Protein from Ganoderma microsporum, Potentiates Cisplatin-Induced Apoptosis via Autophagy in Lung Cancer Cells." in: Molecular pharmaceutics, Vol. 12, Issue 5, pp. 1534-43, (2015) (PubMed).

    Rabionet, Bayerle, Jennemann, Heid, Fuchser, Marsching, Porubsky, Bolenz, Guillou, Gröne, Gorgas, Sandhoff: "Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4792-808, (2015) (PubMed).

    Kashima, Shintani-Ishida, Nakajima, Maeda, Unuma, Uchiyama, Yoshida: "Immunohistochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 44, Issue 7, pp. 779-87, (2014) (PubMed).

    Islam, Shin, Yun, Cho, Seo, Chae, Cho: "The effect of RNAi silencing of p62 using an osmotic polysorbitol transporter on autophagy and tumorigenesis in lungs of K-rasLA1 mice." in: Biomaterials, Vol. 35, Issue 5, pp. 1584-96, (2013) (PubMed).

    Zhang, Morgan, Chen, Choksi, Liu: "Induction of autophagy is essential for monocyte-macrophage differentiation." in: Blood, Vol. 119, Issue 12, pp. 2895-905, (2012) (PubMed).

    Zhou, Kang, Spector: "Production of interferon ? by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy." in: The Journal of infectious diseases, Vol. 205, Issue 8, pp. 1258-67, (2012) (PubMed).

    Xing, Zhang, Li, Zhang, Li, Dang, Li, Fan, Yu, Pei, Zeng: "Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction." in: Autophagy, Vol. 8, Issue 1, pp. 63-76, (2012) (PubMed).

    Song, Lee: "Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis." in: The Journal of biological chemistry, Vol. 286, Issue 18, pp. 15797-805, (2011) (PubMed).

    Tuffy, Concannon, DOrsi, King, Woods, Huber, Ward, Prehn: "Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition." in: Molecular and cellular biology, Vol. 30, Issue 23, pp. 5484-501, (2010) (PubMed).

    Rouschop, van den Beucken, Dubois, Niessen, Bussink, Savelkouls, Keulers, Mujcic, Landuyt, Voncken, Lambin, van der Kogel, Koritzinsky, Wouters: "The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5." in: The Journal of clinical investigation, Vol. 120, Issue 1, pp. 127-41, (2010) (PubMed).

    Byun, Yoon, An, Park, Kang, Kim, Lee: "The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras." in: Carcinogenesis, Vol. 30, Issue 11, pp. 1880-8, (2009) (PubMed).

  • Target
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    Andere Bezeichnung
    LC3 (MAP1LC3A Produkte)
    Synonyme
    ATG8E antikoerper, LC3 antikoerper, LC3A antikoerper, MAP1ALC3 antikoerper, MAP1BLC3 antikoerper, 1010001H21Rik antikoerper, 4922501H04Rik antikoerper, LC3a antikoerper, MGC69006 antikoerper, zgc:77094 antikoerper, MGC89867 antikoerper, MAP1LC3A antikoerper, map1lc3a antikoerper, microtubule associated protein 1 light chain 3 alpha antikoerper, microtubule-associated protein 1 light chain 3 alpha antikoerper, microtubule associated protein 1 light chain 3 alpha S homeolog antikoerper, MAP1LC3A antikoerper, Map1lc3a antikoerper, map1lc3a.S antikoerper, map1lc3a antikoerper
    Hintergrund
    MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
    Gen-ID
    84557
    NCBI Accession
    NP_115903, NP_852610
    UniProt
    Q9H492, Q9GZQ8
    Pathways
    Autophagie
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