CD3 (CD3E) Antikörper

Antigen: CD3 (CD3E)

Synonyme: T3E, TCRE, FLJ18683

Klonalität: Monoklonal (UCHT1)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN376613

Produktbeschreibung

Weitere Bezeichnung: CD3

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: UCHT1

Spezifität: Epsilon chain of the CD3/T cell antigen receptor complex CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.

Anwendungen

Applikationshinweise: To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform to the characteristics of a standard reference reagent. Purified antibody conjugate: <= 1 µ g/10 6 cells, Fluorescein conjugate: 10 µ L/10 6 cells, Biotin conjugate: 10 µ L/10 6 cells, R-phycoerythrin conjugate: 10 µ L/10 6 cells, Allophycocyanin and Allophycocyanin-Cyanine 7 conjugate: 10 µ L/10 6 cells, Spectral Red conjugate: 10 µ L/10 6 cells, Cyanine 5 conjugate: 10 µ L/10 6 cells, R-phycoerythrin-Cyanine 5.5 conjugate: 10 µ L/10 6 cells, R-phycoerythrin-Cyanine 7 conjugate: 10 µ L/10 6 cells, AF488 and AF647 conjugate: 10 µ L/10 6 cells.

Buffer: The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added. Store at 2-8°C. The fluorescein (FITC), Cyanine 5 (CY 5), Alexa Flu

Lagerung: Store at 2-8°C

Forschungsgebiet: Immunologie, Adaptive Immunität, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen

Beschränkungen: Nur für Forschungszwecke einsetzbar