CD3 Antikörper

Produktnummer ABIN376394

Der Maus Monoklonal anti-CD3 Antikörper wird verwendet zum Nachweis von CD3 in Proben von Human. Er wurde validiert für FACS, IP, IHC (fro), WB, ICC, IHC (p), Act und BR.

Kurzübersicht für CD3 Antikörper (ABIN376394)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Activation (Act), Blocking Reagent (BR)

Klon: UCHT1

Produktdetails anti-CD3 Antikörper

Verwendungszweck: Mouse Anti-Human CD3-LE/AF

Produktmerkmale: Low Endotoxin/Azide Free Anti-Human CD3 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, activation, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: Human peripheral blood lymphocytes from a patient with Sezary's syndrome and infant thymocytes

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80 % of normal peripheral blood lymphocytes and on 10-20 % of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation.

Gen-ID: 916

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway