Serotonin Receptor 3A Antikörper (Internal Region)

Produktnummer ABIN374713

Dieser Ziege Polyklonal Antikörper detektiert spezifisch Serotonin Receptor 3A in WB, IF und EIA. Es zeigt Reaktivität gegenüber Proben von Human und Ratte. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für Serotonin Receptor 3A Antikörper (Internal Region) (ABIN374713)

Target: Serotonin Receptor 3A (HTR3A)

Reaktivität: Human, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-Serotonin Receptor 3A Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-GPQDFEKSPR DR

Spezifität: This antibody is expected to recognize all three reported isoforms (NP_998786.2, NP_000860.2, NP_001155244.1).

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence Genename: HTR3A

Anwendungsinformationen

Applikationshinweise: ELISA: 1/128000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Serotonin Receptor 3A Antikörper (ABIN374713)

do Amaral, Ueno, Oliveira, Borsonello, Vanzela, Ribeiro, Alves, Barbosa, Carneiro, Boschero: "Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats." in: The Journal of nutritional biochemistry, Vol. 22, Issue 6, pp. 554-9, (2011) (PubMed).

Lu, Hsieh, Dun, Oprea, Wang, Luo, Lin, Chang, Lee: "Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats." in: Gastroenterology, Vol. 137, Issue 3, pp. 1040-50, (2009) (PubMed).

Details zu Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Hintergrund: 5-hydroxytryptamine (serotonin) receptors is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The 5HT3A receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.Synonyms: 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor

Gen-ID: 3359

NCBI Accession: NP_000860

UniProt: P46098

Pathways: Synaptic Membrane