SETDB2 Antikörper (N-Term)

Produktnummer ABIN374283

Der Ziege Polyklonal anti-SETDB2 Antikörper (ABIN374283) detektiert spezifisch SETDB2 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund und Schwein.

Kurzübersicht für SETDB2 Antikörper (N-Term) (ABIN374283)

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SETDB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SETDB2 Antikörper

Bindungsspezifität: N-Term

Sequenz: GEKNGDAKTF WME-C

Spezifität: This antibody is expected to recognize both reported isoforms (NP_114121.2, NP_001153780.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Porcine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography

Immunogen: Synthetic peptide (GEKNGDAKTFWME-C) from the N-Terminus of the protein sequence according to NP_114121.2, NP_001153780.1. Genename: SETDB2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 1000. Western blot: 0.3-1 μg/mL. Approx 80 kDa band observed in human heart lysates(calculated MW of 81.0 kDa according to NP_114121.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SETDB2

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Andere Bezeichnung: SETDB2 / CLLD8

Hintergrund: Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity.Synonyms: C13orf4, Chronic lymphocytic leukemia deletion region gene 8 protein, Histone-lysine N-methyltransferase SETDB2, KMT1F, Lysine N-methyltransferase 1F, SET domain bifurcated 2

Molekulargewicht: 81.9 kDa (NP_114121.1)

Gen-ID: 83852

NCBI Accession: NP_114121

UniProt: Q96T68