DOCK1 Antikörper (C-Term)

Produktnummer ABIN374114

Der Ziege Polyklonal anti-DOCK1 Antikörper wird verwendet zum Nachweis von DOCK1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Schwein. Er wurde validiert für WB.

Kurzübersicht für DOCK1 Antikörper (C-Term) (ABIN374114)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DOCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DOCK1 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-TTRKQTSVDS GIVQ

Spezifität: This antibody detects DOCK1 at C-term.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_001371.1 Genename: DOCK1

Anwendungsinformationen

Applikationshinweise: Western blot: 3-4 μg/mL. Approx 150-200 kDa band seen in A431 cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Andere Bezeichnung: DOCK1 / DOCK180

Hintergrund: The DOCK1 protein is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. It also functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. The GEF activity of the DOCK1 protein may be enhanced by ELMO1.Synonyms: 180 kDa protein downstream of CRK, Dedicator of cytokinesis protein 1

Gen-ID: 1793

NCBI Accession: NP_001371

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor