P4HB Antikörper

Produktnummer ABIN372745

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch P4HB in WB, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für P4HB Antikörper (ABIN372745)

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P4HB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-P4HB Antikörper

Spezifität: Recognizes endogenous levels of total P4HB.

Kreuzreaktivität (Details): Species reactivity (expected):Monkey, Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide conjugated to KLH derived from the sequence around Proline 329 of Human P4HB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunofluorescence. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM Sodium HEPES, pH 7.5, 150 mM Sodium Chloride, 0.1 mg/mL BSA, 50 % Glycerol

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu P4HB

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Andere Bezeichnung: PDI / P4HB

Hintergrund: P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.Synonyms: Cellular thyroid hormone-binding protein, ER marker, ERBA2L, P4HB, PDI, PDIA1, PO4DB, Prolyl 4-hydroxylase subunit beta, Protein Disulfide Isomerase, Protein disulfide-isomerase, p55

Molekulargewicht: 57 kDa.

Gen-ID: 5034

NCBI Accession: NP_000909

UniProt: P07237

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism