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CD72 Antikörper

CD72 Reaktivität: Maus FACS, Func Wirt: Maus Monoclonal 10-1-D-2 unconjugated
Produktnummer ABIN371001
  • Target Alle CD72 Antikörper anzeigen
    CD72 (CD72 Molecule (CD72))
    Reaktivität
    • 47
    • 18
    • 1
    Maus
    Wirt
    • 37
    • 20
    • 1
    Maus
    Klonalität
    • 37
    • 21
    Monoklonal
    Konjugat
    • 25
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD72 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 24
    • 22
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Spezifität
    This antibody recognises CD72.1/Lyb-2.1 (Mr. 45 kDa). It blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (Ref.1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72. (Ref.1-5)
    Produktmerkmale
    Synonyms: Lyb-2, Ly-32, Ly32, B-Cell marker, B-cell differentiation antigen CD72, Lymphocyte antigen32
    Aufreinigung
    Purified
    Immunogen
    DBA/2 mouse spleen cells. (Ref. 1)
    Klon
    10-1-D-2
    Isotyp
    IgG2b
    Top Product
    Discover our top product CD72 Primärantikörper
  • Applikationshinweise
    Flow Cytometry. (Ref.1,2)Functional Assays: In vitro blocking and proliferation assays. (Ref.2,3)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD72 (CD72 Molecule (CD72))
    Andere Bezeichnung
    CD72 (CD72 Produkte)
    Synonyme
    CD72c antikoerper, Ly-19 antikoerper, Ly-32 antikoerper, Ly-m19 antikoerper, Lyb-2 antikoerper, CD72b antikoerper, LYB2 antikoerper, CD72 antigen antikoerper, CD72 molecule antikoerper, Cd72 antikoerper, CD72 antikoerper
    Hintergrund
    Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (Ref.1,2)Synonyms: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32
    Gen-ID
    100504743
    UniProt
    P21855
    Pathways
    BCR Signaling
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