TRKA Antikörper (AA 789-793)
Kurzübersicht für TRKA Antikörper (AA 789-793) (ABIN363051)
Target
Alle TRKA (NTRK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 789-793
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Spezifität
- The antibody detects endogenous level of total TrkA protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogen
- Peptide sequence around AA 789-793 (P-V-Y-L-D) derived from Human TrkA. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotyp
- IgG
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr681), (Tyr680) antibody
NTRK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 725-821) antibodyNTRK1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 769-796) antibodyNTRK1 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB16572 unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (2nd Extracellular Domain), (AA 342-356) antibodyKO Validated NTRK1 Reaktivität: Ratte WB, IHC, IF, FACS, IC, LCI Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 33-208) antibodyNTRK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (C-Term) antibodyNTRK1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibodyNTRK1 Reaktivität: Human, Maus WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 769-796) antibodyNTRK1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (C-Term) antibodyNTRK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr496) antibodyNTRK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Immunofluorescence: 1:100-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
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Andere Bezeichnung
- TrkA
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Hintergrund
- Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
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Molekulargewicht
- 140 kDa
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NCBI Accession
- NP_001007
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UniProt
- P04629
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Pathways
- RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process
Target
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