Glutamate Receptor 1 Antikörper (AA 861-865)

Produktnummer ABIN362940

Der Kaninchen Polyklonal anti-Glutamate Receptor 1 Antikörper wird verwendet zum Nachweis von Glutamate Receptor 1 in Proben von Human, Ratte und Maus. Er wurde validiert für IF.

Kurzübersicht für Glutamate Receptor 1 Antikörper (AA 861-865) (ABIN362940)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: AA 861-865

Spezifität: The antibody detects endogenous level of total GluR1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen: Peptide sequence around AA 861-865 (R-N-S-G-A) derived from Human GluR1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: GluR1

Hintergrund: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 110 kDa

NCBI Accession: NP_000818

UniProt: P42261

Pathways: PI3K-Akt Signalweg