NEFL Antikörper
Kurzübersicht für NEFL Antikörper (ABIN361352)
Target
Alle NEFL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Specific for the ~68k Neurofilament L protein.
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Kreuzreaktivität
- Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus)
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Aufreinigung
- Protein G purified culture supernatant
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Immunogen
- Preparation of porcine NF-L
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Isotyp
- IgG1
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Applikationshinweise
- Recommended Dilution: WB: 1:1,000 IF: 1:100 Quality Control: Western blots performed on each lot.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- total IgG fraction + 10 mM Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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Andere Bezeichnung
- NEFL
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Hintergrund
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2). Anti-Neurofilament L Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.
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Molekulargewicht
- '68 kDa
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Gen-ID
- 4747
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UniProt
- P02547
Target
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