In den Warenkorb
Bestellen Sie auch über:
+49 (0)241 95 163 153
+49 (0)241 95 163 155

C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Antikörper

Antigen

C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)

Synonyme ABL, JTK7, p150, c-ABL, v-abl, bcr/abl, Abl, c-Abl, AI325092, MGC117749, E430008G22Rik, ABL1, ARG, ABLL, FLJ22224, FLJ31718, FLJ41441, Arg, Abll, AA536808, MGC169395, ABL2, CABL, cb272
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN359968
Menge 0.1 mg  (0.25 mg/ml)
Preis 330,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: c-ABL, p150, JTK7, bcr/abl, Proto-oncogene tyrosine-protein kinase ABL1, Abelson murineleukemia viral oncogene homolog 1
Weitere Bezeichnung ABL1
Gen-ID 25
Swiss-Prot P00519
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the center region of human ABL1.
Kreuzreaktivität Human
Isotyp Ig  (Passende Sekundärantikörper)
Beschreibung The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase thathas been implicated in processes of cell differentiation, cell division, cell adhesion, andstress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, anddeletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation resultsin the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronicmyelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cyclefunction for ABL1.
Spezifität This ABL1 antibody recognizes ABL1 at Center. Species Reactivity: Tested: Human.

Anwendungen

Applikationshinweise ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/10-1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 0.25 mg/ml
Reinigung Purified
Buffer PBS with 0.09% (W/V) Sodium Azide
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)", Typ "Antikörper" finden
Wirte Kaninchen (104), Maus (15)
Reaktivitäten Human (112), Maus (55), Ratte (Rattus) (35), Rind (Kuh) (16), Hund (15), Pferd (15), Schwein (15), Kaninchen (15), Affe (2)
Applikationen Western Blot (WB) (69), Immunhistochemie (Paraffinschnitte) (IHC (p)) (41), Immunhistochemie (IHC) (30), ELISA (26), Immunfluoreszenz (IF) (26), Enzyme Immunoassay (EIA) (18), Immunpräzipitation (IP) (17), Durchflusszytometrie (FACS) (13), Dot Blot (Dot) (8), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Immunodiffusion (ID) (1), Immunoelectron Microscopy (IEM) (1), Neutralisierung (Neut) (1)
Konjugate Biotin (4), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pTyr412 (13), Ab-412 (3), pTyr204 (3), pThr754 (2), pTyr251 (2), pTyr283 (2), C-Term (1), Center (1), N-Term H246 (1), N-Term K219 (1), Y251 (1), Y272 (1), Y276 (1), pSer588 (1), pTyr134 (1), pTyr245 (1), pTyr272 (1), pTyr276 (1), pY134 (1)