OAS3 Antikörper (C-Term)

Produktnummer ABIN358718

Der Kaninchen Polyklonal anti-OAS3 Antikörper wird verwendet zum Nachweis von OAS3 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für OAS3 Antikörper (C-Term) (ABIN358718)

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OAS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-OAS3 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to OAS3.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human OAS3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu OAS3

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Andere Bezeichnung: OAS3

Hintergrund: OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.Synonyms: (2-5')oligo(A) synthetase 3, 2'-5'-oligoadenylate synthetase 3, 2-5A synthetase 3, p100 OAS

Gen-ID: 4940, 9606

UniProt: Q9Y6K5

Pathways: Hepatitis C