HIF1A Antikörper (AA 432-528)
Kurzübersicht für HIF1A Antikörper (AA 432-528) (ABIN2852421)
Target
Alle HIF1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 432-528
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Spezifität
- Reacts with human HIF-1 alpha
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Kreuzreaktivität
- Maus, Rind (Kuh), Kaninchen, Schaf
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Kreuzreaktivität (Details)
- Cross reacts with proteins from monkey, sheep, mouse, rat, rabbit, pig, bovine and ferret.
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Aufreinigung
- Purified (protein A)
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Immunogen
- Fusion protein containing amino acids 432-528 of human HIF-1alpha
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Isotyp
- IgG2b
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ChIP(1:10 - 1:500) GS(1:1 - 1:100) ICC/IF(1:50) IHC(1:20 - 1:50) IP(1:10 - 1:500) WB: (1:500) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.5 mg/mL
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Buffer
- Tris-glycine, 150 mM NaCl, Sodium azide 0.05 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 4°C. Do not freeze.
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- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
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Andere Bezeichnung
- Hypoxia-inducible factor 1-alpha
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Hintergrund
- HIF-1 is a nuclear protein involved in mammalian oxygen homeostasis.This occurs as a posttranslational modification by prolyl hydroxylation. HIF-1 alpha is involved in B-1 B cell homeostasis, Notch signaling pathway and many other biological processes.
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Gen-ID
- 3091
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UniProt
- Q16665
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, Warburg Effekt
Target
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