PDE11A Antikörper (AA 455-468)

Produktnummer ABIN337393

Dieser Ziege Polyklonal Antikörper detektiert spezifisch PDE11A in WB, ELISA, IHC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Hund, Rind (Kuh), Fledermaus, Affe und Schwein.

Kurzübersicht für PDE11A Antikörper (AA 455-468) (ABIN337393)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reaktivität: Human, Hund, Rind (Kuh), Fledermaus, Affe, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PDE11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PDE11A Antikörper

Bindungsspezifität: AA 455-468

Spezifität: Human PDE11A. This antibody is expected to recognise all four reported isoforms (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Pig (100%) Mouse, Rat, Hamster, Horse, Rabbit, Opossum (93%) Xenopus, Stickleback, Pufferfish, Zebrafish (86%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-NSFKESMEKSSYSD from an internal region of human PDE11A (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Pig (100%), Mouse, Rat, Hamster, Horse, Rabbit, Opossum (93%), Xenopus, Stickleback, Pufferfish, Zebrafish (86%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (10 μg/mL), Peptide-ELISA (1:2000), WB (0.5 - 1.5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Andere Bezeichnung: PDE11A

Hintergrund: Name/Gene ID: PDE11A
Subfamily: PDE - cAMP/cGMP dual-specific
Family: Phosphodiesterase

Synonyms: PDE11A, Pde11, PDE11A4, PDE11A1, PPNAD2, PDE11A2, PDE11A3, Phosphodiesterase 11A

Gen-ID: 50940

NCBI Accession: NP_058649, NP_001070665, NP_001070826, NP_001070664

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process