TAR DNA Binding Protein (TARDBP) Antikörper

Antigen: TAR DNA Binding Protein (TARDBP)

Synonyme: ALS10, TDP-43, Tdp43, C85084, 1190002A23Rik, fb77f02, fc52g10, wu:fb77f02, wu:fc52g10, tardbp, MGC53141, TARDBP, TDP43, DKFZp459I2127, MGC129120

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN334503

Produktbeschreibung

Weitere Bezeichnung: TARDBP

Gen-ID: 23435, 230908 (mouse)

Immunogen: Peptide with sequence C-HISNAEPKHNSNRQ, from the internal region of the protein sequence according to NP_031401.1

Beschreibung: All names and symbols: TARDBP, TAR DNA binding protein, ALS10, TDP-43, OTTHUMP00000002171, TAR DNA-binding protein-43. Official Symbol: TARDBP. RefSeq number(s): NP_031401.1

Spezifität: Expected from sequence similarity: Human, Mouse, Dog, Cow

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx. 45kDa band observed in Human lysates of cell line Jurkat (calculated MW of 44.7kDa according to NP_031401.1). Recommended concentration: 0.3-1µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, Transkriptionsfaktoren, DNS/RNS, Hormone, Zytokine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN334503 (0.3 ug/ml) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Zhang, Xu, Dickey et al.: "Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 39, pp. 10530-4, 2007 (PubMed).