Suppressor of Cytokine Signaling 7 (SOCS7) Antikörper

Antigen: Suppressor of Cytokine Signaling 7 (SOCS7)

Synonyme: NAP4, NCKAP4, Nap4, C85125, 2310063P06Rik, Socs7, GB13951, MGC175115, zgc:175115, SOCS6, SOCS4, SOCS7, socs7, AI427843, AU015727, AU015859, MGC143730, MGC143731, 3110032M18Rik, A730004F22Rik, DKFZp686J1568

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN334497

Produktbeschreibung

Weitere Bezeichnung: SOCS7

Gen-ID: 30837

Immunogen: C-DAGRKPKLTRTQS

Beschreibung: All names and symbols: SOCS7, suppressor of cytokine signaling 7, NAP4, Nck, Ash and phospholipase C binding protein. Official Symbol: SOCS7. RefSeq number(s): NP_055413.1

Spezifität: Human

Synonyme: NAP4, NCKAP4, Nap4, C85125, 2310063P06Rik, Socs7, GB13951, MGC175115, zgc:175115, SOCS6, SOCS4, SOCS7, socs7, AI427843, AU015727, AU015859, MGC143730, MGC143731, 3110032M18Rik, A730004F22Rik, DKFZp686J1568

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx. 60kDa band observed in lysates of Daudi (calculated MW of 63.0kDa according to NP_055413.1). Recommended concentration: 1-3µg/ml. An additional band of unknown identity was also consistently observed at 28kDa. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN334497 (1µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Kremer, Adang, Macara: "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7." in: Cell, Vol. 130, Issue 5, pp. 837-50, 2007 (PubMed).