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ENOS Antikörper (pSer1177)

NOS3 Reaktivität: Human, Ratte, Maus IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN319231
  • Target Alle ENOS (NOS3) Antikörper anzeigen
    ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
    Bindungsspezifität
    • 36
    • 26
    • 23
    • 22
    • 16
    • 16
    • 15
    • 14
    • 12
    • 10
    • 10
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1177
    Reaktivität
    • 274
    • 162
    • 162
    • 14
    • 11
    • 10
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 275
    • 37
    • 1
    Kaninchen
    Klonalität
    • 277
    • 36
    Polyklonal
    Konjugat
    • 128
    • 27
    • 16
    • 14
    • 13
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 5
    Dieser ENOS Antikörper ist unkonjugiert
    Applikation
    • 262
    • 104
    • 99
    • 91
    • 79
    • 57
    • 37
    • 32
    • 25
    • 24
    • 15
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Phospho-eNOS antibody (AP08011PU) detects endogenous levels of eNOS only when phosphorylated at serine 1177.
    Aufreinigung
    Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human eNOS around the phosphorylation site of Serine 1177 (T-Q-Sp-F-S).
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    Discover our top product NOS3 Primärantikörper
  • Applikationshinweise
    Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Embedded Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at-20 °C.
  • Target
    ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
    Andere Bezeichnung
    NOS3 (NOS3 Produkte)
    Synonyme
    ECNOS antikoerper, eNOS antikoerper, 2310065A03Rik antikoerper, Nos-3 antikoerper, ecNOS antikoerper, EC-NOS antikoerper, NOSIII antikoerper, cNOS antikoerper, NOS antikoerper, NOS3 antikoerper, eNos antikoerper, ENOS antikoerper, nitric oxide synthase 3 antikoerper, nitric oxide synthase 3, endothelial cell antikoerper, NOS3 antikoerper, Nos3 antikoerper, nos3 antikoerper
    Hintergrund
    ENOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial
    Gen-ID
    4846
    NCBI Accession
    NP_000594
    UniProt
    P29474
    Pathways
    ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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