Tryptophan Hydroxylase 1 Antikörper

Produktnummer ABIN319127

Der Schaf Polyklonal anti-Tryptophan Hydroxylase 1 Antikörper wird verwendet zum Nachweis von Tryptophan Hydroxylase 1 in Proben von Human und Ratte. Er wurde validiert für WB und IHC (fro).

Kurzübersicht für Tryptophan Hydroxylase 1 Antikörper (ABIN319127)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reaktivität: Human, Ratte

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Tryptophan Hydroxylase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Tryptophan Hydroxylase 1 Antikörper

Spezifität: This antibody recognises Tryptophan Hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.

Aufreinigung: Affinity chromatography

Immunogen: Recombinant rabbit Tryptophan Hydroxylase purified from E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections: 1: 1000. Western Blot: 1: 1000, detects a band of approximately 55 kDa in human dorsal Raphenucleus lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Andere Bezeichnung: Tryptophan 5-Hydroxylase 1 (TPH1)

Hintergrund: Synonyms: TPRH, TRPH, Tryptophan 5-monooxygenase 1

Gen-ID: 7166

NCBI Accession: NP_004170

UniProt: P17752

Pathways: Feeding Behaviour