CD11c Antikörper

Produktnummer ABIN317135

Der Maus Monoklonal anti-CD11c Antikörper wird verwendet zum Nachweis von CD11c in Proben von Human. Er wurde validiert für FACS, IHC (fro) und Func.

Kurzübersicht für CD11c Antikörper (ABIN317135)

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11c Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: CBR-p150-4G1

Produktdetails anti-CD11c Antikörper

Spezifität: This antibody specifically recognises CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. This antibody does not recognise CD11a, CD11b or CD18.

Produktmerkmale: Synonyms: Integrin alpha-X, Leu-M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain,Leukocyte adhesion receptor p150, 95, CD11 antigen-like family member C

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Recombinant human CD11c

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Immunohistochemistry on frozen sections: 5 - 10g/mL. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Andere Bezeichnung: CD11c

Hintergrund: CD11c is a 150 kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen.Synonyms: CD11 antigen-like family member C, ITGAX, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150 95

Gen-ID: 3687

UniProt: P20702

Pathways: Komplementsystem, Activated T Cell Proliferation, Integrin Complex