TARDBP Antikörper (AA 1-260)
Kurzübersicht für TARDBP Antikörper (AA 1-260) (ABIN306465)
Target
Alle TARDBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-260
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Verwendungszweck
- Human TDP-43/TARDBP antibody
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Aufreinigung
- Purified
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Immunogen
- Recombinant human TARDBP (1-260aa) purified from E. coli
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Isotyp
- IgG1 kappa
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP Reaktivität: Human WB, IF, ELISA, IP, IHC (p), RNAi Wirt: Maus Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibodyTARDBP Reaktivität: Human WB, IP, RIP Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP Reaktivität: Human WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibodyTARDBP Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKD Validated TARDBP Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 23GB4730 unconjugated Recombinant Antibody
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution 1:1000(W.B), Recommended dilution 1:100(IHC)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Andere Bezeichnung
- TDP-43/TARDBP
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Hintergrund
- TAR DNA binding protein (TARDBP), also known as TDP-43, is a cellular protein. TARDBP was identified as the disease accumulating protein in patients with frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions (FTLD-U) and in amyotrophic lateral sclerosis (ALS). TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. In addition, this protein regulates alternate splicing of the cystic fibrosis transmembrane receptor (CFTR) gene.
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NCBI Accession
- NP_031401
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Target
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