Der Maus Monoklonal anti-DcR2 Antikörper (Klon TRAIL-R4-01) (ABIN301992) detektiert spezifisch DcR2 in FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
TNFRSF10D
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
TRAIL-R4-01
APC
Applikationshinweise
Flow cytometry: Recommended dilution: 1-4 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4
Konservierungsmittel
Azide free
Handhabung
Do not freeze
Lagerung
4 °C
Informationen zur Lagerung
Store at 2-8°C. Do not freeze.
Target
DcR2 (TNFRSF10D)
(Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
Andere Bezeichnung
CD264
Hintergrund
TNF receptor superfamily member 10d,TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).,TNFRSF10D, DcR2, TRUNDD, TRAILR4