TNFRSF10B Antikörper (AA 388-407)

Produktnummer ABIN290834

Der Kaninchen Polyklonal anti-TNFRSF10B Antikörper wird verwendet zum Nachweis von TNFRSF10B in Proben von Human. Er wurde validiert für WB, FACS, IHC, ICC und IHC (p).

Kurzübersicht für TNFRSF10B Antikörper (AA 388-407) (ABIN290834)

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF10B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TNFRSF10B Antikörper

Bindungsspezifität: AA 388-407

Spezifität: A peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor. The same sequence is found in isoform 1 at amino acids 417-436.

Aufreinigung: Protein G purified

Immunogen: A peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor (1,2). The same sequence is found in isoform 1 at amino acids 417-436.

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: Flo, ICC, IHC, IHC-P (10 μg/mL), WB (1:500 - 1:1000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Andere Bezeichnung: TNFRSF10B / Killer / DR5

Hintergrund: Name/Gene ID: TNFRSF10B
Family: TNF Receptor

Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9

Gen-ID: 8795

UniProt: O14763

Pathways: p53 Signalweg, Apoptose, Positive Regulation of Endopeptidase Activity