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beta-Catenin (CTNNB1) Antikörper

Antigen

beta-Catenin (CTNNB1)

Synonyme
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... mehr anzeigen
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN272182
Menge 100 µg  (1,0 mg/ml)  (Varianten)
Preis 320,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: CTNNB1, CTNNB, beta-1 Catenin, beta catenin, beta-Catenin 1, Catenin-beta 1
Weitere Bezeichnung Catenin beta-1
Swiss-Prot P35222
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Beschreibung The catenins, alpha, beta and gamma, are proteins which bind to the highly conserved,intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes playan important role mediating cellular adhesion. alpha-catenin was initially described as anE-cadherin associated protein, and since has been shown to associate with other membersof the cadherin family, such as N-cadherin and P-cadherin. beta-catenin associates withthe cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin asan adhesion molecule. beta-catenin has also been found in complexes with the tumorsuppressor protein APC. gamma-catenin, also known as plakoglobin, is a protein thatbinds with α-catenin and N-cadherin. It has been shown that the transmembranephosphatase PTPµ associates with catenin/cadherin complexes and may regulate complexsignaling.
Spezifität Catenin-beta1 (F660) antibody detects endogenous levels ofCatenin-beta1 protein. Species: Human, Mouse, Rat. Others not tested.
Synonyme CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Anwendungen

Applikationshinweise ELISA: 1: 20000~1: 40000. WB: 1: 500~1: 1000. IHC: 1: 50~1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 1,0 mg/ml
Reinigung Aff - Purified
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Lagerung Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Forschungsgebiet Signaltransduktion
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "beta-Catenin (CTNNB1)", Typ "Antikörper" finden
Wirte Kaninchen (186), Maus (62)
Reaktivitäten Human (230), Maus (154), Ratte (Rattus) (137), Huhn (29), Hund (13), Rind (Kuh) (8), Schwein (6), Xenopus laevis (5), Hamster (2), Affe (1), Kaninchen (1), Schaf (1)
Applikationen Western Blot (WB) (219), Immunfluoreszenz (IF) (72), Immunpräzipitation (IP) (63), Enzyme Immunoassay (EIA) (51), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunhistochemie (IHC) (40), ELISA (30), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Dot Blot (Dot) (8), Immunzytochemie (ICC) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Elektromobilitäts-Experimente (EMSA) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (5), Cy3 (2), FITC (2), HRP (2), Alexa Flour 488 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer33 (10), pSer37 (10), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), C-Term (5), pSer33/37 (5), pThr41/Ser45 (5), pThr41/pSer45 (5), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer45 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pTyr489 (1)