TFAP2A Antikörper
Kurzübersicht für TFAP2A Antikörper (ABIN265311)
Target
Alle TFAP2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody detects endogenous levels of TFAP2A / AP-2 alpha protein (region surrounding Lys431).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
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Reinheit
- > 95 % pure by SDS-PAGE
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Applikationshinweise
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
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Andere Bezeichnung
- TFAP2A / AP-2 alpha
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Hintergrund
- The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer.AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.Synonyms: AP-2 transcription factor, AP2, AP2TF, Activating enhancer-binding protein 2-alpha, Activator protein 2, TFAP2
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Molekulargewicht
- approx. 50 kDa
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Gen-ID
- 7020
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NCBI Accession
- NP_001027451
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UniProt
- P05549
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Pathways
- Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism
Target
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