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Tumor Necrosis Factor Receptor Superfamily Member 10d (TNFRSF10D) Antikörper

Antigen

Tumor Necrosis Factor Receptor Superfamily Member 10d (TNFRSF10D)
Synonyme DCR2, CD264, TRUNDD, TRAILR4, TNFRSF10D
Klonalität Monoklonal (TRAIL-R4-01)
Wirt
Reaktivität
Alternativen

Human
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN238513
Menge 0.1 mg  (1.0 mg/ml)
Preis 230,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper zurück nach oben

Produktmerkmale Synonyms: TNFRSF10D, DCR2, TRAIL-R4, TRUNDD, Decoy receptor 2, TRAIL receptor 4, Tumor necrosisfactor receptor superfamily member 10D, TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor with a truncated death domain
Weitere Bezeichnung CD264 / TRAILR4
Swiss-Prot Q9UBN6
Immunogen TRAIL-R4 (aa 1-210) - hIgGhc fusion protein.
Kreuzreaktivität Human
Isotyp IgG1  (Passende Sekundärantikörper)
Klon TRAIL-R4-01
Beschreibung TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs toreceptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in manytumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated deathdomain, thus it is unable to induce apoptosis and serves as a negative regulator ofapoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependentmanner and prevents its corecruitment with death receptor 4 (DR4).
Spezifität The antibody TRAIL-R4-01 reacts with TRAIL-R4, a 42 kDa transmembrane protein expressedon various blood cells. Species: Human. Others not tested.

Anwendungen
Alternativen Sekundärantikörper zurück nach oben

Applikationshinweise Suitable for use in Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 1.0 mg/ml
Reinigung Azide Free
Buffer PBS, pH 7.4 without preservatives.
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
Forschungsgebiet Signaltransduktion, Apoptose/Nekrose
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper zurück nach oben

Alternativen zu Antigen "Tumor Necrosis Factor Receptor Superfamily Member 10d (TNFRSF10D)", Typ "Antikörper" finden
Wirte Kaninchen (12), Maus (9), Ziege (1), Ratte (1)
Reaktivitäten Human (21), Maus (2), Ratte (Rattus) (1)
Applikationen Western Blot (WB) (13), Durchflusszytometrie (FACS) (9), Enzyme Immunoassay (EIA) (5), Immunfluoreszenz (IF) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Immunpräzipitation (IP) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (1)
Konjugate FITC (1), PE (1)