HLA Class I alpha G (HLAG) Antikörper

Antigen: HLA Class I alpha G (HLAG)

Klonalität: Monoklonal (G233)

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Durchflusszytometrie (FACS), Immunpräzipitation (IP)

Produktnummer: ABIN238406

Produktbeschreibung

Produktmerkmale: Synonyms: HLA-6.0, HLAG, MHC class I antigen G, HLA class I histocompatibility antigen

Weitere Bezeichnung: HLA class I alpha G / HLA-G

Gen-ID: 3135

Swiss-Prot: P17693

Immunogen: Murine L cells transfected with both human beta2-microglobulin and HLA-G

Kreuzreaktivität: Human

Isotyp: IgG2a  (Passende Sekundärantikörper)

Klon: G233

Beschreibung: HLA G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of aheavy chain (with a1, a2, a3 domains) and a light chain (beta 2 microglobulin). Alternatesplicing provides both soluble and membrane bound forms of HLA G, with two solubleisoforms and four membrane bound isoforms. HLA G may be part of the fetal protectionsystem and is expressed on fetal derived placental cells.

Spezifität: The antibody G233 recognizes several isoforms of HLA-G expressed in all populations ofextravillous trophoblast (cell columns, interstitial trophoblast, endovascular trophoblast,placental bed giant cells). HLA-G belongs to the nonclassical MHC Class I molecules (MHCClass Ib). The antibody G233 has been found not to cross-react with any other MHC Class Iantigens (HLA-A, -B, -C, -E, -F). Species Reactivity: Tested: Human

Anwendungen

Applikationshinweise: Flow Cytometry. Immunoprecipitation. ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Reinigung: Aff - Purified

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar