HLA Class I alpha G (HLAG) Antikörper

Antigen: HLA Class I alpha G (HLAG)

Klonalität: Monoklonal (01G)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Durchflusszytometrie (FACS), Immunfluoreszenz (IF), Immunpräzipitation (IP)

Produktnummer: ABIN238362

Produktbeschreibung

Produktmerkmale: Synonyms: HLA-6.0, HLAG, MHC class I antigen G, HLA class I histocompatibility antigen

Weitere Bezeichnung: HLA class I alpha G / HLA-G

Swiss-Prot: P17693

Immunogen: HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected withand expressing genes encoding HLA-G and human beta2-microglobulin.

Kreuzreaktivität: Human

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 01G

Beschreibung: HLA G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of aheavy chain (with a1, a2, a3 domains) and a light chain (beta 2 microglobulin). Alternatesplicing provides both soluble and membrane bound forms of HLA G, with two solubleisoforms and four membrane bound isoforms. HLA G may be part of the fetal protectionsystem and is expressed on fetal derived placental cells.

Spezifität: The antibody 01G recognizes membrane-bound form of HLA-G (full-length HLA-G1), but notsoluble forms. HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical)and it is expressed on the surface of trophoblast cells. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: Flow Cytometry. Immunoprecipitation. Immunohistochemistry (frozen sections). Immunocytochemistry. ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Reinigung: Purified

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar