TNFRSF4 Antikörper

Produktnummer ABIN206653

Dieser Maus Monoklonal Antikörper detektiert spezifisch TNFRSF4 in WB und FACS. Es zeigt Reaktivität gegenüber Proben von Cat.

Kurzübersicht für TNFRSF4 Antikörper (ABIN206653)

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Reaktivität: Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: 7D6

Produktdetails anti-TNFRSF4 Antikörper

Spezifität: Recognizes feline CD134, otherwise known as OX40, a 43kD type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.

Keine Kreuzreaktivität: Maus

Aufreinigung: Protein A purified

Immunogen: CHO-derived feline CD134-Fc fusion protein.

Type of Immunogen: Fusion protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo, WB (1 μg/mL)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. Western Blot: LS-C44970 detects a band of approximately 43kD.

Kommentare:

Target Species of Antibody: Cat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Andere Bezeichnung: TNFRSF4 / CD134 / OX40

Hintergrund: Name/Gene ID: TNFRSF4
Family: TNF Receptor

Synonyms: TNFRSF4, ACT35 antigen, ATC35 antigen, CD134, ACT35, OX40, OX40 antigen, OX40L receptor, OX40 homologue, CD134 antigen, OX40 cell surface antigen, TXGP1L

Gen-ID: 7293

UniProt: P43489

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints