TNFRSF4 Antikörper (C-Term)

Produktnummer ABIN3044553

Produktdetails anti-TNFRSF4 Antikörper

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Bindungsspezifität: AA 232-254, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 4(TNFRSF4) detection. Tested with WB, IHC-P in Human.

Sequenz: AILLALYLLR RDQRLPPDAH KPP

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 4(TNFRSF4) detection. Tested with WB, IHC-P in Human.
Gene Name: mor necrosis factor receptor superfamily, member 4
Protein Name: Tumor necrosis factor receptor superfamily member 4

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CD134/OX40 (232-254aa AILLALYLLRRDQRLPPDAHKPP), different from the related mouse sequence by ten amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Andere Bezeichnung: TNFRSF4 (TNFRSF4 Produkte)

Synonyme: TNFRSF4 antikoerper, ACT35 antikoerper, CD134 antikoerper, Ly-70 antikoerper, Ox40 antikoerper, TXGP1L antikoerper, Txgp1 antikoerper, OX40 antikoerper, TNF receptor superfamily member 4 antikoerper, tumor necrosis factor receptor superfamily, member 4 antikoerper, TNFRSF4 antikoerper, Tnfrsf4 antikoerper

Hintergrund: Tumor necrosis factor receptor superfamily, member 4, also known as ACT35 or CD134, is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. CD134 was mapped to 1p36 by fluorescence in situ hybridization. CD134 is the primary receptor for feline immunodeficiency virus. And CD134 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.

Synonyms: ACT 35 antibody|ACT35 antibody|ACT35 antigen antibody|ATC35 antigen antibody|CD 134 antibody|CD134 antibody|CD134 antigen antibody| Lymphoid activation antigene ACT35 antibody| OX 40 antibody|OX40 antibody|OX40 antigen antibody|OX40 cell surface antigen antibody| OX40 homologue antibody|OX40L receptor antibody|TAX transcriptionally activated glycoprotein 1 receptor antibody|TAX transcriptionally-activated glycoprotein 1 receptor antibody|TNFRSF 4 antibody|TNFRSF4 antibody|TNR4_HUMAN antibody|Tumor necrosis factor receptor superfamily member 4 antibody|Txgp 1l antibody|Txgp1 antibody|Txgp1l antibody

Gen-ID: 7293

UniProt: P43489

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints