Linker For Activation of T Cells (LAT) Antikörper

Antigen: Linker For Activation of T Cells (LAT)

Synonyme: LAT1, pp36, MGC108666, LAT, MGC157208, lat

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN185255

Produktbeschreibung

Weitere Bezeichnung: LAT1

Gen-ID: 27040

Immunogen: C-GAPDYENLQELN

Format: Affinity-purified

Beschreibung: All names and symbols: LAT1, LAT, linker for activation of T cells, pp36, 36 kDa phospho-tyrosine adaptor protein. Official Symbol: LAT. RefSeq number(s): NP_055202.1, NP_001014987.1, NP_001014989.1, NP_001014988.1. Gene ontology terms: SH3/SH2 adaptor protein activity, immune response, integral to membrane, signal transduction

Spezifität: This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1). Human, Mouse, Rat 262 aa

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:2,000. Western Blot: Approx 35kDa band observed in Human PBMC lysates (predicted MW of 30kDa according to NP_055202.1). Recommended for use at 1-3µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN185255 (0.01µg/ml) staining of peripheral blood mononucleocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Finco, Kadlecek, Zhang et al.: "LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway." in: Immunity, Vol. 9, Issue 5, pp. 617-26, 1998 (PubMed).