Myotubularin 1 (MTM1) Antikörper

Antigen: Myotubularin 1 (MTM1)

Synonyme: CNM, MTMX, XLMTM, MTM1, MGC123266, zgc:123266, DKFZp469D2412, Mtm, AF073996, KIAA4176, mKIAA4176, MGC97721, mtm1, MGC115089

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN184636

Produktbeschreibung

Weitere Bezeichnung: MTM1

Gen-ID: 4534

Immunogen: C-SSPSQMMPHVQTHF

Format: Affinity-purified

Beschreibung: All names and symbols: MTM1, myotubular myopathy 1, CNM, MTMX, XLMTM, myotubularin. Official Symbol: MTM1. RefSeq number(s): NP_000243.1. Gene ontology terms: protein serine/threonine phosphatase activity, prenylated protein tyrosine phosphatase activity, cell growth and/or maintenance, muscle development, protein amino acid dephosphorylation, cellular_component unknown, hydrolase activity

Spezifität: Human 603 aa

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 70kDa band observed in lysates of Human Skeletal Muscle and of cell line HepG2 (calculated MW of 69.9kDa according to NP_000243.1). Recommended concentration: 0.3-1µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Forschungsgebiet: Stammzellen, Metabolismus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN184636 (0.3µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Laporte, Hu, Kretz et al.: "A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast." in: Nature genetics, Vol. 13, Issue 2, pp. 175-82, 1996 (PubMed).