TNFRSF18 Antikörper (C-Term)

Produktnummer ABIN184156

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TNFRSF18 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TNFRSF18 Antikörper (C-Term) (ABIN184156)

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TNFRSF18 Antikörper

Bindungsspezifität: C-Term

Sequenz: LRSQCMWPRE TQLLLEVPPS TEDARSCQFP EEERGERSAE EKGRLGDLWV

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNFRSF18. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 241 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Andere Bezeichnung: TNFRSF18

Hintergrund: The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Alias Symbols: AITR, GITR, CD357, GITR-D
Protein Interaction Partner: LNX1, TRAF3, TRAF2, TRAF1, TNFSF18, TNFRSF18,
Protein Size: 241

Molekulargewicht: 26 kDa

Gen-ID: 8784

NCBI Accession: NM_004195, NP_004186

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints