Meiotic Recombination 11 (MRE11) Antikörper

Antigen: Meiotic Recombination 11 (MRE11)

Synonyme: ATLD, HNGS1, MRE11, MRE11B, DmelCG16928, CG16928, GB17160, Mre11, MDK4.8, MDK4_8, meiotic recombination 11, NGS1, XRS4, RAD58, Mer11, mre11

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: ELISA, Western Blot (WB), Immunpräzipitation (IP)

Produktnummer: ABIN129647

Produktbeschreibung

Weitere Bezeichnung: Mre11 (S.Cerevisiae)

Gen-ID: NP_013951

Swiss-Prot: P32829

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 578-590 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein. Protein Sequence: Saccharomyces cerevisiae Mre11, 692 aa, predicted MW 77.6 kDa 1 mdypdpdtir ilittdnhvg ynendpitgd dswktfhevm mlaknnnvdm vvqsgdlfhv 61 nkpskkslyq vlktlrlccm gdkpcelell sdpsqvfhyd eftnvnyedp nfnisipvfg 121 isgnhddasg dsllcpmdil hatglinhfg kviesdkikv vpllfqkgst klalyglaav 181 rderlfrtfk dggvtfevpt mregewfnlm cvhqnhtght ntaflpeqfl pdfldmviwg 241 hehecipnlv hnpiknfdvl qpgssvatsl ceaeaqpkyv fildikygea pkmtpiplet 301 irtfkmksis lqdvphlrph dkdatskyli eqveemirda neetkqklad dgegdmvael 361 pkplirlrvd ysapsntqsp idyqvenprr fsnrfvgrva ngnnvvqfyk krspvtrskk 421 sgingtsisd rdveklfses ggelevqtlv ndllnkmqls llpevglnea vkkfvdkdek 481 talkefishe isnevgilst neeflrtdda eemkalikqv kransvrptp pkendetnfa 541 fngngldsfr ssnrevrtgs pditqshvdn esrithisqa esskptskpk rvrtatkkki 601 pafsdstvis daenelgdnn daqddvdide ndiimvstde edasygllng rktktktrpa 661 astktasrrg kgrasrtpkt dilgsllakk rk

Format: Liquid (sterile filtered)

Beschreibung: Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability. Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function. This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.

Spezifität: This affinity-purified antibody is directed against Saccharomyces cerevisiae Mre11 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest that little cross reactivity should be expected with this protein from other sources.

Anwendungen

Applikationshinweise: Recommended Dilutions: ELISA 1:10,000 - 1:50,000 WESTERN BLOT 1:200 - 1:2,000 IF MICROSCOPY User Optimized OTHER APPLICATIONS User Optimized. Note: This affinity purified antibody has been tested for use in ELISA and by ChIP assay. Specific conditions for reactivity should be optimized by the end user.

Konzentration: 1.19 mg/ml (by UV absorbance at 280 nm)

Buffer: Stabilizer: None. Preservative: 0.01% (w/v) Sodium Azide. Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2.

Lagerung: Store vial at -20° C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of opening.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Meiotic Recombination 11 (MRE11) antibody