IL1R1 Antikörper (Extracellular Domain)

Produktnummer ABIN120264

Der Hamster Monoklonal anti-IL1R1 Antikörper (Klon JAMA-147) (ABIN120264) detektiert spezifisch IL1R1 in IP und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für IL1R1 Antikörper (Extracellular Domain) (ABIN120264)

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser IL1R1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Flow Cytometry (FACS)

Klon: JAMA-147

Produktdetails anti-IL1R1 Antikörper

Bindungsspezifität: Extracellular Domain

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Extracellular domain of murine IL-1R. Spleen cells from immunised Armenian Hamster were fused with cells of the mouse P3X63.Ag 8-653 myeloma cell line.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL1R1

Target: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Andere Bezeichnung: CD121a / IL1R1

Hintergrund: CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members, IL-1 alpha, IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a.Synonyms: IL-1R-alpha, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I

Gen-ID: 10090

UniProt: P13504

Pathways: NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints