CIITA Antikörper (N-Term)

Produktnummer ABIN116527

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CIITA in WB, IP und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CIITA Antikörper (N-Term) (ABIN116527)

Target: CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIITA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Produktdetails anti-CIITA Antikörper

Bindungsspezifität: AA 1-333, N-Term

Sequenz: Peptide: IKDNKELPQY LALTTR

Aufreinigung: This product was prepared from monospecific antiserum by delipidation and defibrination.

Immunogen: Peptide corresponding to a region near the N-terminal end of the human CIITA gene conjugated to Keyhole Limpet Hemocyanin (KLH).

Anwendungsinformationen

Applikationshinweise: Suitable for Immunoblotting (1/500), ELISA and Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 90.0 mg/mL (by Refractometry)

Handhabung: Avoid repeated freezing or thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store original vial at 2-8 °C. After reconstitution store stock solution at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu CIITA

Target: CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))

Andere Bezeichnung: CIITA / C2TA

Hintergrund: The transactivator CIITA regulates basal and interferon-induced expression of Major Histocompatibility Complex class II genes. CIITA restores expression of all MHC class II gene expression in mutant cells and corrects regulatory defects of MHC class II genes. Antibodies to this transactivator are useful in the study of diseases of pathological MHC class II expression. Antigen can be obtained from Raji cell lysates. Typically levels of CIITA expression are too low to detect endogenous levels of protein expression. Transiently transfected cells are usually employed to study this transcription factor.Synonyms: MHC class II transactivator, MHC2TA

Gen-ID: 4261

NCBI Accession: NP_000237

UniProt: P33076

Pathways: Cancer Immune Checkpoints