MCM7 Antikörper

Produktnummer ABIN115134

Der Maus Monoklonal anti-MCM7 Antikörper (Klon 47DC141) (ABIN115134) detektiert spezifisch MCM7 in WB, IHC (p), IP und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MCM7 Antikörper (ABIN115134)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MCM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 47DC141

Produktdetails anti-MCM7 Antikörper

Spezifität: This antibody reacts with a 80 kDa protein known as hCDC47.
Cellular Localization: Nuclear

Aufreinigung: Purified

Immunogen: BALB/C mice were injected with recombinant human CDC47 protein.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Western Blot. Immunohistochemistry on paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Breast carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Andere Bezeichnung: MCM7

Hintergrund: HCDC47 is a member of MCM family, which allows DNA to replicate once per cell cycle. Expression of hCDC47 protein has been found in the nuclei of proliferative components of normal lymph nodes, bone marrow, epidermis and mucosa. Malignant tumors from several organs contain more nuclear hCDC47-positive cells than their normal counterparts.Synonyms: CDC47, CDC47 homolog, DNA replication licensing factor MCM7, MCM2, P1.1-MCM3, minichromosome maintenance complex component 7

Gen-ID: 4176

NCBI Accession: NP_005907

UniProt: P33993

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA