CTXB Antikörper

Produktnummer ABIN113086

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CTXB in EIA und IP. Es zeigt Reaktivität gegenüber Proben von Vibrio cholerae.

Kurzübersicht für CTXB Antikörper (ABIN113086)

Target: CTXB (CtxB Gene Product (CTXB))

Reaktivität: Vibrio cholerae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTXB Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunoprecipitation (IP)

Produktdetails anti-CTXB Antikörper

Spezifität: Beta subunit of Cholera toxin.

Aufreinigung: Protein A chromatography.

Immunogen: Purified choleragenoid.

Anwendungsinformationen

Applikationshinweise: ELISA: Titer: >1: 1,000. Also suitable for conjugation purposes. Immunoprecipitates toxin in gel techniques.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 4-5 mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 0.01 M PBS, pH 7.2 with 0.09 % sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTXB

Target: CTXB (CtxB Gene Product (CTXB))

Andere Bezeichnung: Cholera Enterotoxin Subunit B

Hintergrund: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

Gen-ID: 2613962

NCBI Accession: NP_231099

UniProt: P01556