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Kallikrein-Related Peptidase 3 (KLK3) Antikörper

Antigen

Kallikrein-Related Peptidase 3 (KLK3)

Synonyme APS, PSA, hK3, KLK2A1, KLK3, KLKB1
Klonalität Monoklonal (214)
Wirt
Reaktivität
Alternativen

Human

Applikation
Alternativen Enzyme Immunoassay (EIA), ELISA (Detektionsantikörper)
Produktnummer ABIN112463
Menge 1 mg  (1.0 mg/ml)
Preis 210,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Weitere Bezeichnung Kallikrein-3 / PSA / KLK3
Swiss-Prot P07288
Immunogen Highly pure PSA from human prostate.
Isotyp IgG1  (Passende Sekundärantikörper)
Klon 214
Beschreibung Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis andsome have potential as novel cancer and other disease biomarkers. This gene is one of thefifteen kallikrein subfamily members located in a cluster on chromosome 19. Its proteinproduct is a protease present in seminal plasma. It is thought to function normally in theliquefaction of seminal coagulum, presumably by hydrolysis of the high molecular massseminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, isuseful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of thisgene generates two transcript variants encoding different isoforms. Additional transcriptvariants have been described, but it is unclear if these transcripts are normally expressedor if they are specific to benign or malignant tumors.
Spezifität This antibody is specific for prostate specific antigen, recognising both the free andcomplexed forms. This antibody can be used as a coating antibody in a two site assay withcatalogue number BM696 as the detection reagent. Species: Human. Others not tested.

Anwendungen

Applikationshinweise ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 1.0 mg/ml
Buffer PBS, pH 7.0 containing 0.09% Sodium Azide
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Forschungsgebiet Zell-/Gewebemarker, Krebs
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Kallikrein-Related Peptidase 3 (KLK3)", Typ "Antikörper" finden
Wirte Maus (102), Kaninchen (38), Ziege (4), Schaf (3), Huhn (1)
Reaktivitäten Human (115), Maus (1)
Applikationen Enzyme Immunoassay (EIA) (54), Immunhistochemie (Paraffinschnitte) (IHC (p)) (51), Western Blot (WB) (43), ELISA (36), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (23), Immunhistochemie (IHC) (8), Immunpräzipitation (IP) (7), Immunfluoreszenz (IF) (4), Radioimmunoassay (RIA) (3), ELISA (Fangantikörper) (2), Durchflusszytometrie (FACS) (2), Zell-ELISA (cELISA) (1), Dot Blot (Dot) (1), ELISA (Detektionsantikörper) (1), Funktionale Studien (Func) (1), Immunoassay (IA) (1), Immunzytochemie (ICC) (1), Immunoradiometrisches Assay (IRMA) (1), Lateral Flow Messung (LF) (1)
Konjugate Biotin (3), HRP (3)
Epitope Total (13), C-Term (2)