Integrin, AlphaIIb Antikörper

Antigen: Integrin, AlphaIIb

Klonalität: Monoklonal (CA3)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (IHC), Western Blot (WB)

Produktnummer: ABIN108423

Produktbeschreibung

Immunogen: Monoclonal antibody to aIIb integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Partially purified platelet glycoprotein IIb/IIIa complex was used as an immunogen.

Format: Purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: CA3

Beschreibung: Monoclonal Antibody to Human Integrins

Spezifität: The antibody reacts with the aIIb-subunit of the b-integrins. Reacts specifically with platelets, megakaryocytes and leukemic cells able to megakaryocytic differentiation

Anwendungen

Applikationshinweise: No reactivity with paraffin sections. Working dilution in western blotting is at least 1:1000

Lagerung: This product should be stored at +2 C to +8 C

Forschungsgebiet: Extrazelluläre Matrix

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Transformed CHO cells (MAb CA3, aIIb-Integrin)

Publikationen

Publikationen: Ylanne J, Cheresh DA, Virtanen I: "Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cells." in: Blood, Vol. 76, Issue 3, pp. 570-7, 1990 (PubMed).

Ylanne J, Hormia M, Jarvinen M et al.: "Platelet glycoprotein IIb/IIIa complex in cultured cells. Localization in focal adhesion sites in spreading HEL cells." in: Blood, Vol. 72, Issue 5, pp. 1478-86, 1988 (PubMed).

Tani T, Ylanne J, Virtanen I: "Expression of megakaryocytic and erythroid properties in human leukemic cells." in: Exp Hematol, Vol. 24, Issue 2, pp. 158-68, 1996 (PubMed).