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IL-3 Antikörper (Biotin)

IL-3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1043808
  • Target Alle IL-3 Antikörper anzeigen
    IL-3 (Interleukin 3 (IL-3))
    Reaktivität
    • 74
    • 41
    • 23
    • 4
    Human
    Wirt
    • 75
    • 28
    • 17
    • 2
    • 2
    Kaninchen
    Klonalität
    • 81
    • 43
    Polyklonal
    Konjugat
    • 70
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser IL-3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 89
    • 46
    • 26
    • 26
    • 21
    • 14
    • 14
    • 11
    • 11
    • 10
    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Biotin Conjugated Anti-Human IL-3 Antibody Biotin is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-3 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
    Produktmerkmale
    The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.
    Aufreinigung
    purified
    Immunogen
    Anti-Human IL-3 (RABBIT) Antibody Biotin Conjugated was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-3 protein.
    Immunogen Type: RecombinantProtein
    Isotyp
    IgG
    Top Product
    Discover our top product IL-3 Primärantikörper
  • Applikationshinweise
    This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to human IL-3 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Kommentare

    Gene Name: IL3

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

  • Target
    IL-3 (Interleukin 3 (IL-3))
    Andere Bezeichnung
    IL-3 (IL-3 Produkte)
    Synonyme
    BPA antikoerper, Csfmu antikoerper, HCGF antikoerper, Il-3 antikoerper, MCGF antikoerper, PSF antikoerper, IL-3 antikoerper, MULTI-CSF antikoerper, interleukin 3 antikoerper, interleukin 3 (colony-stimulating factor, multiple) antikoerper, Il3 antikoerper, IL3 antikoerper
    Hintergrund
    The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.
    Synonyms: Burst promoting activity, Colony stimulating factor, Eosinophil colony stimulating factor, Hematopoietic growth factor, IL 3, Interleukin 3
    Gen-ID
    3562
    NCBI Accession
    NP_000579
    UniProt
    P08700
    Pathways
    JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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