Dieses Anti-ZIC1-3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZIC1-3 in IHC und WB. Geeignet für Human.
Produktnummer ABIN351417
Kurzübersicht für ZIC1-3 Antikörper (C-Term) (ABIN351417)
Target
ZIC1-3 (Zic1/2/3)
(Zic Family Member 1/2/3 (Zic1/2/3))
Reaktivität
Human
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
Bindungsspezifität
C-Term
Verwendungszweck
Rabbit antibody to ZIC1-3
Spezifität
Specific for ZIC1 2 3.
Kreuzreaktivität
Human, Maus, Ratte
Kreuzreaktivität (Details)
Other species not yet tested.
Aufreinigung
IgG
Immunogen
A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.
Isotyp
IgG
Applikationshinweise
IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Handhabung
Avoid freeze and thaw cycles.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit
12 months
Target
ZIC1-3 (Zic1/2/3)
(Zic Family Member 1/2/3 (Zic1/2/3))
Andere Bezeichnung
ZIC1-3
Hintergrund
Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation. Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs including asplenia or polysplenia symmetric liver intestinal malrotation and abnormal lung lobation.