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ZIC1-3 Antikörper (C-Term)

Dieses Anti-ZIC1-3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZIC1-3 in IHC und WB. Geeignet für Human.
Produktnummer ABIN351417

Kurzübersicht für ZIC1-3 Antikörper (C-Term) (ABIN351417)

Target

ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Applikation

Immunohistochemistry (IHC), Western Blotting (WB)
  • Bindungsspezifität

    C-Term

    Verwendungszweck

    Rabbit antibody to ZIC1-3

    Spezifität

    Specific for ZIC1 2 3.

    Kreuzreaktivität

    Human, Maus, Ratte

    Kreuzreaktivität (Details)

    Other species not yet tested.

    Aufreinigung

    IgG

    Immunogen

    A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.

    Isotyp

    IgG
  • Applikationshinweise

    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

    Handhabung

    Avoid freeze and thaw cycles.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))

    Andere Bezeichnung

    ZIC1-3

    Hintergrund

    Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation. Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs including asplenia or polysplenia symmetric liver intestinal malrotation and abnormal lung lobation.

    UniProt

    O60481
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