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ZFPM1 Proteine

(Zinc Finger Protein, Multitype 1 (ZFPM1))

Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

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ZFPM1 Protein (AA 1-1006) (Strep Tag)

custom-made ZFPM1 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Produktnummer ABIN3092576

15.754,29 €

Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt

250 μg

Lieferung nach: Deutschland

Lieferung in 51 bis 61 Werktagen

Details

ZFPM1 Protein (AA 1-995) (Strep Tag)