MDM4-binding Protein ELISA Kit

5 products by 3 suppliers: ChromoTek | Abnova | Assay Biotechnology
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MDM4 ELISA Kit
$380.00
96 tests
Human
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MDM4 ELISA Kit
$380.00
96 tests
Mouse (Murine)
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MDM4 ELISA Kit
$380.00
96 tests
Rat (Rattus)
Recommendations are based on data provided indicating:
  • ELISA Kit Sensitivity
    The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiment Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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MDM4-binding Protein Antigen Profile

Beschreibung des Gens

This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latter's degradation. So this protein can reverse MDM2-targeted degradation of p53, while maintaining suppression of p53 transactivation and apoptotic functions. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with MDM4-binding Protein

  • MDM4, p53 regulator S homeolog (mdm4.S) ELISA Kit
  • MDM4, p53 regulator (MDM4) ELISA Kit
  • MDM4, p53 regulator (Mdm4) ELISA Kit
  • MDM4, p53 regulator (mdm4) ELISA Kit
  • transformed mouse 3T3 cell double minute 4 (Mdm4) ELISA Kit
  • mdmx ELISA Kit
  • HDMX ELISA Kit
  • MDMX ELISA Kit
  • MRP1 ELISA Kit
  • wu:fa09h09 ELISA Kit
  • wu:fi33d10 ELISA Kit
  • 4933417N07Rik ELISA Kit
  • AA414968 ELISA Kit
  • AL023055 ELISA Kit
  • AU018793 ELISA Kit
  • AU021806 ELISA Kit
  • C85810 ELISA Kit
  • Mdmx ELISA Kit

Bezeichner auf Proteinebene für MDM4-binding Protein

double minute 4 protein , mdm2-like p53-binding protein , p53-binding protein Mdm4 , protein Mdm4 , MDM4-related protein 1 , double minute 4, human homolog of; p53-binding protein , protein Mdmx , Mdm4, transformed 3T3 cell double minute 4, p53 binding protein , double minute 4 homolog , transformed mouse 3T3 cell double minute 4

GENE ID SPEZIES
398466 Xenopus laevis
4194 Homo sapiens
478939 Canis lupus familiaris
514225 Bos taurus
304798 Rattus norvegicus
334932 Danio rerio
17248 Mus musculus
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