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Cullin 1 Proteine

7 Treffer:

Cullin 1 (CUL1) (AA 1-776) protein (His tag) Protein

Crystallography grade CUL1 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3092025
$15,464.90
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 70 Werktagen

Cullin 1 (CUL1) (AA 1-776) protein (His tag) Protein

Crystallography grade CUL1 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3137494
$15,464.90
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 70 Werktagen

Cullin 1 (CUL1) (AA 1-776) protein (GST tag) Protein

CUL1 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
Pubmed 1
Produktnummer ABIN1350756
$498.33
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
2 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

Cullin 1 (CUL1) Protein Protein

CUL1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Produktnummer ABIN2128764
$532.32
Zzgl. Versandkosten $45.00
50 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 9 bis 11 Werktagen

Cullin 1 (CUL1) (AA 1-250) protein (T7 tag,His tag) Protein

CUL1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % ELISA, IP, SDS, WB
Produktnummer ABIN6239084
$324.00
Zzgl. Versandkosten $45.00
50 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 12 bis 15 Werktagen

Cullin 1 (CUL1) (AA 1-410) protein (His tag) Protein

CUL1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667243
$553.85
Zzgl. Versandkosten $45.00
50 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 15 bis 19 Werktagen

Cullin 1 (CUL1) protein (Myc-DYKDDDDK Tag) Protein

CUL1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Produktnummer ABIN2712629
$1,019.70
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
20 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 Werktagen
  • Typ Protein
    • Protein
  • Target Cullin 1 (CUL1)
    • Cullin 1 (CUL1)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • SARS-CoV-2 Spike
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase (lipA)
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Aspartate Carbamoyltransferase (PYRB)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • Epidermal Growth Factor Receptor (EGFR)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Adenosylhomocysteinase (AHCY)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • Programmed Cell Death 1 (PDCD1)
    • SARS-CoV-2 Spike S1
    • Thymidine Kinase 1, Soluble (TK1)
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
    • Insulin-Like Growth Factor 1 (IGF1)
  • Anwendung
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reaktivität
    • Human
    • Maus
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Wirt
    • Escherichia coli (E. coli)
    • Insektenzellen
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 1-776
    • AA 1-250
    • AA 1-410
  • Konjugat
    • Unkonjugiert
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • T7 tag,His tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
  • Grade
    • Crystallography grade

Cullin 1 (CUL1) Protein Überblick

Protein Überblick

Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5 and probably NFKB2. SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF(FBXW2) directs ubiquitination of GCM1. SCF(FBXO32) directs ubiquitination of MYOD1. SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5. SCF(FBXO33) directs ubiquitination of YBX1. SCF(FBXO11) does not seem to direct ubiquitination of TP53. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'\; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110 (By similarity).

Alternative names and synonyms associated with Cullin 1 (CUL1)

  • cullin 1 (CUL1) Antikörper
  • cullin-1 (LOC100282292) Antikörper
  • cullin 1 (cul1) Antikörper
  • cullin-1 (ATEG_00491) Antikörper
  • cullin-1 (EDI_072700) Antikörper
  • cullin-1 (EDI_264400) Antikörper
  • Cullin 1 (SJAG_02591) Antikörper
  • Cullin-1 (BDBG_03785) Antikörper
  • cullin 1 (Cul1) Antikörper
  • cullin 1a (cul1a) Antikörper
  • cullin 1 S homeolog (cul1.S) Antikörper
  • Cullin-1 (cul-1) Antikörper
  • cullin 1b (cul1b) Antikörper
  • ATCUL1 Antikörper
  • AUXIN RESISTANT 6 Antikörper
  • AXR6 Antikörper
  • Cul-1 Antikörper
  • cul1 Antikörper
  • cullin-1 Antikörper
  • cullin 1 Antikörper
  • LOC100282292 Antikörper
  • T10P11.26 Antikörper
  • T10P11_26 Antikörper
  • wu:fc13a10 Antikörper
  • wu:fi43h07 Antikörper
  • wu:fj43a08 Antikörper
  • zgc:55483 Antikörper
  • zgc:55747 Antikörper
  • zgc:77500 Antikörper
  • zgc:111899 Antikörper

Bezeichner auf Proteinebene für Cullin 1 Proteine (CUL1)

CUL-1 , cullin-1 , Cullin-1 , Cell division control 53 homolog

GENE ID SPEZIES
8454 Homo sapiens
100282292 Zea mays
734121 Xenopus (Silurana) tropicalis
100173991 Pongo abelii
4355245 Aspergillus terreus NIH2624
5880828 Entamoeba dispar SAW760
5884109 Entamoeba dispar SAW760
7047697 Schizosaccharomyces japonicus yFS275
8509782 Ajellomyces dermatitidis SLH14081
26965 Mus musculus
323883 Danio rerio
362356 Rattus norvegicus
734414 Xenopus laevis
420783 Gallus gallus
475512 Canis lupus familiaris
407228 Bos taurus
825648 Arabidopsis thaliana
176466 Caenorhabditis elegans
406816 Danio rerio
2542393 Schizosaccharomyces pombe 972h-
100345752 Oryctolagus cuniculus
100727053 Cavia porcellus
101106584 Ovis aries musimon

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