anti-Aurora Kinase C (AURKC) Antikörper

Bezeichnung:: anti-Aurora Kinase C Antikörper (AURKC)

Auf www.antikoerper-online.de finden Sie aktuell 139 Aurora Kinase C (AURKC) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Aurora Kinase C Proteine (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 164 Aurora Kinase C Produkte verfügbar.

Synonyme:: AIE1, AIE2, AIK3, ARK-3, ARK3, AurC, AURKC, aurora-C, IAK3, SPGF5, Stk13

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	AURKC	6795	Q9UQB9
	AURKC	20871
	AURKC	292554
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human Aurora Kinase C Antikörper:

anti-Mouse (Murine) Aurora Kinase C Antikörper:

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Am meisten referenzierte anti-Aurora Kinase C Antikörper

Human Polyclonal Aurora Kinase C Primary Antibody für WB - ABIN1882164 : Kimura, Matsuda, Yoshioka, Okano: Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3. in The Journal of biological chemistry 1999 (PubMed)
Show all 3 Pubmed References
Cow (Bovine) Polyclonal Aurora Kinase C Primary Antibody für WB - ABIN2785453 : Lee, Lim, Park, Lee, Han, Kim, Cheang, Lee, Lee, Ko, Jang, Kim, Miniaci, Bartsch, Kim, Bailey, Kandel, Kaang: Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia. in Cell 2007 (PubMed)
Show all 2 Pubmed References
Human Polyclonal Aurora Kinase C Primary Antibody für WB - ABIN390979 : Burum-Auensen, Skotheim, Schjølberg, Røislien, Lothe, Clausen: Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. in Journal of carcinogenesis 2010 (PubMed)
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Human Polyclonal Aurora Kinase C Primary Antibody für ELISA, WB - ABIN4282476 : Dieterich, Zouari, Harbuz, Vialard, Martinez, Bellayou, Prisant, Zoghmar, Guichaoua, Koscinski, Kharouf, Noruzinia, Nadifi, Sefiani, Lornage, Zahi, Viville, Sèle, Jouk, Jacob, Escalier, Nikas et al.: The Aurora Kinase C c.144delC mutation causes meiosis I arrest in men and is frequent in the North African population. ... in Human molecular genetics 2009 (PubMed)
Human Polyclonal Aurora Kinase C Primary Antibody für WB - ABIN4890463 : Doyle, Lee, Selesniemi, Styer, Rueda: The impact of vitrification on murine germinal vesicle oocyte In vitro maturation and aurora kinase A protein expression. in Journal of assisted reproduction and genetics 2014 (PubMed)

Weitere Antikörper gegen Aurora Kinase C Interaktionspartner

Human Aurora Kinase C (AURKC) Interaktionspartner

The epigenetic targets AURKB (zeige AURKB Antikörper), AURKC and DNMT3B (zeige DNMT3B Antikörper), and the global DNA methylation (zeige HELLS Antikörper) profile are regulated during HIV-1 replication in CD4 (zeige CD4 Antikörper)+ T cells, and this regulation can be influenced by the activation state of the cell at the time of infection.
The data suggest that AKA (zeige NEUROG1 Antikörper) is the vertebrate ancestral gene, and that AKB and AKC resulted from gene duplication in placental mammals.
Two novel DMRs, located in RPS6KA4/MIR1237 and the AURKC promoter, were found to be hypermethylated in WT
Identification and characterization of AURKB (zeige AURKB Antikörper) and AURKC variants associated with maternal aneuploidy has been reported.
Aurora-C interactions with members of the Chromosome Passenger Complex (CPC), Survivin and Inner Centromere Protein (INCENP (zeige INCENP Antikörper)) in reference to known Aurora-B (zeige AURKB Antikörper) interactions to understand the functional significance of Aurora-C overexpression in human cancer cells, is reported.
Patients presenting with a monomorphic teratozoospermia such as globozoospermia or macrospermia with more than 85% of the spermatozoa presenting this specific abnormality have been analyzed permitting to identify several key genes for spermatogenesis such as AURKC and DPY19L2 (zeige DPY19L2 Antikörper).
Homozygous c.144delC mutation in AURKC gene in infertile men with macrozoospermia in the Tunisian population
AURKC mutations are more frequent than Klinefelter syndrome and constitute the leading genetic cause of infertility in North African men.
Low AURKC expression is associated with cancer.
Overexpression of AURKC is associated with breast tumors.

Mouse (Murine) Aurora Kinase C (AURKC) Interaktionspartner

findings demonstrate that maternal RNAs regulate AURKC localization and activity in mouse oocytes
The high sequence similarity among the AURK family members has made discerning the individual kinase functions in meiosis challenging. Technical limitations in specifically targeting AURKB (zeige AURKB Antikörper) or AURKC using small-molecule inhibitors and compensatory abilities in single-knockout animals add to this challenge...proper regulation of AURKA (zeige AURKA Antikörper) expression is crucial for spindle formation in meiosis
Three of these mutations AURKC c.144delC (AURKC p.L49Wfs22), AURKC c.686G > A (AURKC p.C229Y) and AURKC c.744C > G (AURKC p.Y248*) are the focus of this study. AURKC p.L49Wfs22 is a loss-of-function mutant that perturbs localization of the chromosomal passenger complex (CPC), AURKC p.C229Y is a hypomorph that cannot fully support cell-cycle progression, and AURKC p.Y248* fails to support chromosome segregation.
These data uncover a role for haspin (zeige GSG2 Antikörper) as a regulator of bipolar spindle assembly by regulating AURKC function at acentriolar microtubule-organizing centers in oocytes.
these data suggest that mammalian oocytes contain AURKC to efficiently execute meiosis I and ensure high-quality eggs necessary for sexual reproduction.
These findings suggest a model for the presence of AURKC in oocytes: that AURKC compensates for loss of AURKB (zeige AURKB Antikörper) through differences in both message recruitment and protein stability.
Overexpressed Aurora-C (aurkc) is an oncogene (zeige RAB1A Antikörper). Overexpression of Aurora-C induces abnormal cell division resulting in centrosome amplification and multinucleation. Cells overexpressing active Aurora-C induced tumour formation.
Conditional deletion of aurora B in somatic cells that do not express aurora C results in chromosomal misalignment and lack of chromosome segregation.
Aurora-C, but not Aurora-B, plays essential roles in female mouse meiosis.
role in regulating the cleavage furrow-specific vimentin (zeige VIM Antikörper) phosphorylation in the cytokinetic process

Cow (Bovine) Aurora Kinase C (AURKC) Interaktionspartner

AURKB (zeige AURKB Antikörper), AURKC, and Thr (zeige TRH Antikörper)-phosphorylated AURKA (zeige AURKA Antikörper) were detected at a contractile ring/midbody during the first polar body extrusion.

Aurora Kinase C (AURKC) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Aurora Kinase C (AURKC)

aurora kinase C (AURKC) Antikörper
aurora kinase C (Aurkc) Antikörper

AIE1 Antikörper
AIE2 Antikörper
AIK3 Antikörper
ARK-3 Antikörper
ARK3 Antikörper
AurC Antikörper
AURKC Antikörper
aurora-C Antikörper
IAK3 Antikörper
SPGF5 Antikörper
Stk13 Antikörper

Bezeichner auf Proteinebene für AURKC

aurora kinase C , ARK-3 , aurora 3 , aurora-related kinase 3 , aurora/IPL1-related kinase 3 , aurora/IPL1/EG2 protein 2 , serine/threonine kinase 13 (aurora/IPL1-like) , serine/threonine-protein kinase 13 , serine/threonine-protein kinase aurora-C , aurora B , aurora/Ipl1/Eg2 protein 1 , serine/threonine kinase 13 (aurora/IPL-like)

GENE ID	SPEZIES
740217	Pan troglodytes
100343856	Oryctolagus cuniculus
709801	Macaca mulatta
6795	Homo sapiens
20871	Mus musculus
292554	Rattus norvegicus
618599	Bos taurus

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